A new tetracyclic diterpenoid from the seeds of Euphorbia lathyris
نویسندگان
چکیده
منابع مشابه
Euphorbia factor L8: a diterpenoid from the seeds of Euphorbia lathyris
THE TITLE COMPOUND [SYSTEMATIC NAME: (2S*,3S*,4R*,5R*,9S*,11S*,15R*)-5,15-diacet-oxy-3-nicotino-yloxy-14-oxolathyra-6(17),12(E)-diene], C(30)H(37)NO(7), was isolated from the seeds of Euphorbia lathyris. The tricyclic diterpenoid molecule contains an 11-membered ring, a five-membered ring exhibiting an envelope conformation and a three-membered ring. The 11-membered ring is cis-fused with the t...
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One new diterpene ester with a tricyclic lathyrane-or myrsinol-type skeleton has been isolated fromEuphorbia decipiensBoiss. &Buhse. In addition to one new, the known constituents -amyrin, -amyrin acetate, methyl (2,4-dihydroxy-3-formyl-6-methoxy) phenyl ketone (2), and 1,1-bis (2,6-dihydroxy-3-acetyl-4-methoxyphenyl)methane (3) have been isolated from the same source. The structure elucidation...
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The seed oil of Euphorbia lathyris L. contains a series of macrocyclic diterpenoids known as Euphorbia factors. They are the current industrial source of ingenol mebutate, which is approved for the treatment of actinic keratosis, a precancerous skin condition. Here, we report an alcohol dehydrogenase-mediated cyclization step in the biosynthetic pathway of Euphorbia factors, illustrating the or...
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Phytochemical investigation on the seeds of Caesalpinia decapetala led to the isolation of a new cassane diterpenoid with an unusual O bridge between C-19 and C-20, named phanginin Q (1), together with three known cassane diterpenoids, caesaljapin (2), caesaldekarin A (3), and caesaldekarin B (4). The structure of the new compound was elucidated by spectroscopic methods, including (1)H NMR, (13...
متن کاملAnalysis and determination of diterpenoids in unprocessed and processed Euphorbia lathyris seeds by HPLC–ESI-MS
Euphorbia lathyris (Caper spurge) is a toxic and potent Chinese materia medica (T/PCMM). This study sought a method for identifying five diterpenoids (Euphorbia factors L1-L3, L7a and L8) with the spectra of UV and mass, quantifying three diterpenoids L1, L2, and L8 in crude extracts of unprocessed and processed E. lathyris seeds by liquid chromatography/electrospray ionization mass spectrometr...
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ژورنال
عنوان ژورنال: Journal of Chemical Research
سال: 2020
ISSN: 1747-5198,2047-6507
DOI: 10.1177/1747519819901101